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Better Breathing, Better Health
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REASONS TO INVEST
TEAM
Michael Chu • Co-Founder and CEO
Michael has worked closely with the Makani Science team from day one to develop the Makani Science Respiratory Monitoring System. He has also actively participated in the business development side of the company, establishing partnerships for future collaborations and research opportunities.
Michael participated in Y-Combinator and MedTech Innovator as part of their 2021 summer cohort where he helped raised additional funding for the company. In Q4 of 2021, Michael was selected as the full time CEO for Makani Science.
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Ray Chan • Board Chairman
Ray has a 30+ year track record of successful business execution and of being a startup queen/kingmaker. Ray has personally made over 300 investments and is well-known for rewarding shareholders with exceptional financial returns.
As the co-founder of Koa Accel and Managing Director of the Koa Accel Venture Fund, Ray is excited to combine all of his expertise and passions to transform life-saving MedTech ideas into thriving commercial ventures.
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Greg Buchert • Board Director
Greg was a founding executive for CalOptima, a public managed care organization where he served as Chief Operating Officer and Medical Director. He began his professional career as a pioneer in Pediatric Emergency Medicine. His previous positions include work as a Principal Consultant with Health Management Associates, a national healthcare consulting firm. Greg started his career as a Pediatric Emergency Physician serving in leadership positions at two children’s hospitals and as administrative director of a medical group.
He is a Fellow of the American College of Emergency Physicians and American Academy of Pediatrics. Greg has a passion for innovation, the expanded use of technology in healthcare, improving quality of care and heath equity.
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*Information from Globe Newswire (Source)
Overview
Better Breathing, Better Health
*The above is a product still currently under development and is not yet available on the market.
The Makani Science Respiratory Monitor was developed to improve respiratory monitoring by making it:
- More accurate (Directly Measure Breathing)
- Convenient (Wireless and Compact)
- Accessible (Easily Adaptable with Other Systems)
- Comfortable (Soft and Flexible Sensor)
- Easy to Use (Simple Interface)
We plan submit our premarket notification to the FDA early 2023 and hope to launch our product Q3 2023. We will target three major areas that would benefit from better respiratory monitoring:
- Medical procedures where patient monitoring could be made safer by providing an earlier and more accurate alert for respiratory abnormalities.
- Respiratory disease management by analyzing the breathing patterns of patients and telling them when they should be getting help will help to improve the patient's quality of life.
- Breathing management in health, wellness, and fitness where feedback on the user's breathing can help improve their quality of life.
Makani Science is in the process of finalizing a licensing agreement with UC Irvine for the exclusive license to use their family of seven patents around the core sensor technology for monitoring breathing. Makani Science would be able to sublicense the technology, and payments and royalties would be made based on set milestones. UC Irvine would receive a small equity stake in Makani Science.
The Problem & Our solution
Wireless Technology for Better Monitoring of Breathing
It only takes 4 minutes for brain damage to occur after you stop breathing; death is almost guaranteed after 10 minutes. This means every second counts when a patient stops breathing.
It is a shocking reality that in the clinical setting, a vital sign as important as respiration is often poorly monitored. Breath rate is a neglected vital sign, mostly because current monitors, such as pulse oximetry and capnography, are inconvenient, bulky, inaccurate, or have delayed response times (Source | Source | Source). This has been a contributing factor to repeated, potentially preventable, patient complications every year. Outside of the hospital, there are very few wearable technologies that can measure breathing accurately, making this a vital sign relatively untapped.
Makani Science novel sensor component
Due to the unique features of the Makani Science sensor technology – novel, compact, postage-sized, and flexible – shown above, the Makani Science monitoring system overcomes these deficiencies, allowing for direct monitoring of breathing in a more accurate, convenient, and comfortable way.
We believe that because of our unique sensor design and small form factor, the Makani Science Respiration Monitor has the potential to help improve the current state of the art in respiration monitoring and unlock breathing applications never before realized.
The animations above show the convenience of the Makani Science Respiration System, wireless and convenient. The product is still currently under development and is not yet available on the market.
the market & Our Traction
Growing Demand and Promising Technology
Our initial market will target procedures where patients are sedated, and their breathing may be at risk. Surprisingly, anesthesiologists are not always present to monitor these patients, and sadly, deaths have been repeatedly attributed to improper respiratory monitoring (Source).
For this application, we believe the Makani Science Respiration Monitor can improve the safety of the patients and function as an early alert system for breathing abnormalities. This global anesthesia and respiratory device market is predicted to reach $38.2 billion by 2023 (Source).
Disease Management
Another critical area where the Makani Science Respiration Monitor could disrupt the market is in the disease management sector. There are many diseases that affect our breathing such as COPD, asthma, sleep apnea, and more recently COVID – to name a few.
Responding quickly to changes in the patient's condition is essential for their health. The Makani Science Respiration Monitor could potentially track and manage patient breathing, improving their quality of life. The respiratory device for disease management market is predicted to reach $21.6 Billion by 2023 (Source).
Wellness and Mindfullness
In addition, the wellness, mindfulness, and fitness market have enormous potential for our sensor. As stress and anxiety increase in our society, we believe people will want to start managing their mental health through biofeedback and proper breathing control.
We believe our sensor, in conjunction with the right App, will be the perfect platform to provide information to the user on how well they are breathing to optimize stress reduction (Source | Source). The consumer health and wellness market is predicted to reach $55.8 Billion by 2023 (Source).
*The product is still currently under development and is not yet available on the market.
Total Market
Due to its differentiating features of being small, flexible, and comfortable, the Makani Science sensor is suitable for wear in clinical settings or home use and can be incorporated into other sensors as well. In total, the potential market for all targeted areas could be over $100 Billion in 2023!
Our Traction and Testimonials
Makani Science has also been accepted into well-known accelerators including Y-Combinator and MedTech Innovators.
*The above testimonials may not be representative of the opinions of other medical experts or the experiences of other customers and is not a guarantee of future performance or success.
Why Invest
Monitoring a Critical Life-Sustaining Vital Sign with Opportunity for Expansion
*The product is still currently under development and is not yet available on the market.
Whether making sedated procedures safer, managing respiratory diseases, and potentially saving lives, the Makani Science Respiration Monitor can make a neglected vital sign more accessible to the world.
With numerous applications for our product, we are presented with an opportunity to tap into this large multi-billion dollar space and can elevate it to new levels with the Makani Science Respiration Monitor, while saving and improving patient lives.
Join the movement toward better breathing and better health and invest in Makani Science today.
ABOUT
HEADQUARTERS
5270 California Ave Ste 300
Irvine, CA 92617
WEBSITE
View Site
TERMS
Makani Science
Overview
PRICE PER SHARE
$0.67
DEADLINE
Mar. 31, 2023 at 6:59 AM UTC
VALUATION
$11.72M
FUNDING GOAL
$10K - $1.23M
Breakdown
MIN INVESTMENT
$249.91
MAX INVESTMENT
$1,234,999.61
MIN NUMBER OF SHARES OFFERED
14,925
MAX NUMBER OF SHARES OFFERED
1,843,283
OFFERING TYPE
Equity
SHARES OFFERED
Common Stock
Maximum Number of Shares Offered subject to adjustment for bonus shares
*Maximum number of shares offered subject to adjustment for bonus shares. See Bonus info below.
Voting Rights of Securities Sold in this Offering
Voting Proxy. Each Subscriber shall appoint the Chief Executive Officer of the Company (the “CEO”), or his or her successor, as the Subscriber’s true and lawful proxy and attorney, with the power to act alone and with full power of substitution, to, consistent with this instrument and on behalf of the Subscriber, (i) vote all Securities, (ii) give and receive notices and communications, (iii) execute any instrument or document that the CEO determines is necessary or appropriate in the exercise of its authority under this instrument, and (iv) take all actions necessary or appropriate in the judgment of the CEO for the accomplishment of the foregoing; provided, however, that the CEO’s ability to exercise the foregoing powers shall be conditioned upon the unanimous approval of the Board of Directors of the Company. The proxy and power granted by the Subscriber pursuant to this Section are coupled with an interest. Such proxy and power will be irrevocable. The proxy and power, so long as the Subscriber is an individual, will survive the death, incompetency and disability of the Subscriber and, so long as the Subscriber is an entity, will survive the merger or reorganization of the Subscriber or any other entity holding the Securities. However, the Proxy will terminate upon the closing of a firm-commitment underwritten public offering pursuant to an effective registration statement under the Securities Act of 1933 covering the offer and sale of Common Stock or the effectiveness of a registration statement under the Securities Exchange Act of 1934 covering the Common Stock.
Investment Incentives and Bonuses*
Time-Based Perks
Friends and Family - First 7 days | 10% bonus shares
Super Early Bird - First 30 days | 5% bonus shares
Volume-Based Perks
Tier 1 Perk — Invest $500+ and receive 2% bonus shares
Tier 2 Perk — Invest $1000+ and receive 5% bonus shares
Tier 3 Perk — Invest $5,000+ and receive 10% bonus shares
Tier 4 Perk — Invest $10,000+ and receive 15% bonus shares
Tier 5 Perk — Invest $20,000+ and receive 20% bonus shares
*In order to receive perks from an investment, one must submit a single investment in the same offering that meets the minimum perk requirement. Bonus shares from perks will not be granted if an investor submits multiple investments that, when combined, meet the perk requirement. All perks occur when the offering is completed.
The 10% StartEngine Owners' Bonus
Makani Science will offer 10% additional bonus shares for all investments that are committed by investors that are eligible for the StartEngine Crowdfunding Inc. OWNer's bonus.
This means eligible StartEngine shareholders will receive a 10% bonus for any Common Stock shares they purchase in this offering. For example, if you buy 100 shares of Common Stock at $0.67 / share, you will receive 110 shares, meaning you'll own 110 shares for $67. Fractional shares will not be distributed and share bonuses will be determined by rounding down to the nearest whole share.
This 10% Bonus is only valid during the investors eligibility period. Investors eligible for this bonus will also have priority if they are on a waitlist to invest and the company surpasses its maximum funding goal. They will have the first opportunity to invest should room in the offering become available if prior investments are canceled or fail.
Investors will receive the highest single bonus they are eligible for among the bonuses based on the amount invested and time of offering elapsed (if any). Eligible investors will also receive the Owner’s Bonus in addition to the aforementioned bonus.
Irregular Use of Proceeds
PRESS
ALL UPDATES
03.30.23
Last Chance to Invest--Less than 1 Day!
Less than 1 Day to Invest!
Hi all,
This is your last chance to invest in Makani Science. Don't miss this opportunity and invest today!
02.24.23
Better Breathing, Better Health
Whether it's making sedated procedures safer, managing respiratory diseases, or potentially saving lives, the Makani Science Respiration Monitor can make a neglected vital sign more accessible to the world.
Invest Today! Join the movement toward better breathing.
02.23.23
Accepted into UC Launch
Hi everyone,
We are excited to announce that we've been selected to be a part of UC Launch, a highly selective accelerator within the University of California universities. We are one of 20 out of hundreds of applications that got chosen!
"LAUNCH is the University of California’s leading accelerator, designed to transform early-stage startups into fundable companies."
During Fall 2022, over 160+ companies raised over $725 million cumulatively. We look forward to growing and developing further through this program.
02.21.23
Notice of Material Change in Offering
[The following is an automated notice from the StartEngine team].
Hello! Recently, a change was made to the Makani Science offering. Here's an excerpt describing the specifics of the change:
Campaign is extending their end date by 30 days
When live offerings undergo changes like these on StartEngine, the SEC requires that certain investments be reconfirmed. If your investment requires reconfirmation, you will be contacted by StartEngine via email with further instructions.
02.09.23
3 Important Facts about Breathing
Take a look at these 3 important facts about breathing!
02.06.23
Deadly Dentistry
One of our goals at Makani Science is to make sedation procedures safer. There is no doubt that medicine has improved greatly in the last couple of decades. However, there are still ways procedures could be made safer. Here’s an in-depth investigation Dallas Morning News published about safety concerns in the dental area: https://interactives.dallasnews.com/2015/deadly-dentistry/
We hope our breathing monitor can address some of these concerns!
02.03.23
Letter from the CEO
Hi everyone!
This is Michael Chu, CEO of Makani Science. I wanted to thank everyone for their continued support and, introduce myself in this update. I am originally from northern California but after graduating from UC San Diego with a degree in Bioengineering and getting my doctoral degree at UC Irvine, I am enjoying life in southern California. I am a co-inventor and one of the original founders of Makani Science. Most importantly I just got married this past year!
As the CEO for Makani Science, these are the values I approach the company with every day:
• I believe in teamwork and respect – the team is key to the success of the company.
• Evidence-based science is important – data is key to showing that our product works.
• I believe in earning the trust of our employees, customers, and investors - Trust is hard to earn and I strive to be a company of integrity.
I understand investing your hard-earned money into a startup can be a difficult choice, so please ask any questions you may have to help make the decision easier. My team and I are here to make sure you make the most informed decision possible.
I truly appreciate your support and time and please stay safe and healthy!
Sincerely,
Michael Chu
01.30.23
Breathing Article
Check out this link on how breathing can reduce stress!
https://hbr.org/2020/09/research-why-breathing-is-so-effective-at-reducing-stress
01.27.23
Novel Sensor
|
Hi Everyone! I wanted to highlight the novel postage-size sensor used in our system. Instead of being rigid and hard, (like a circuit board) our sensors are soft and elastic, like a rubber band. This will make the sensor much more comfortable to wear and expands the market opportunity into other previously untapped fields. Share this with someone who would be interested in a new type of sensor!
|
01.26.23
Early Bird Special
Our early bird special is about to expire in less than 5 days.
Take advantage of it now and get bonus shares!
REWARDS
10%
Stack Venture Club & Rewards!
Members get an extra 10% shares in addition to rewards below!
Venture Club
Venture Club Members earn 10% bonus shares on top of this and all eligible investments for an entire year. Not a member? Sign up at checkout ($275/year).
$500
Tier 1 Perk
Invest $500+ and receive 2% bonus shares
$1,000
Tier 2 Perk
Invest $1000+ and receive 5% bonus shares
$5,000
Tier 3 Perk
Invest $5,000+ and receive 10% bonus shares
$10,000
Tier 4 Perk
Invest $10,000+ and receive 15% bonus shares
$20,000
Tier 5 Perk
Invest $20,000+ and receive 20% bonus shares
JOIN THE DISCUSSION
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Richard Murray
2 years ago
When do you anticipate approval by the FDA or have you submitted your product to them yet? What's the lifespan of the wearable before replacement is recommended and the approximate cost of all consumables to the end user?
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James Henley
2 years ago
Who is your competition? And what sets you apart from them? (Is anyone else working on a similar device that is different than current CPO and capnography?)
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Jada Nix
2 years ago
Do you have any peer-reviewed manuscripts published on this technology?
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Arthur Robertson
2 years ago
Are there any family members that are on staff that is related to any executive member. This makes me uncomfortable as an investor seeing that you could be just using the funds to give a job to support family.
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Arthur Robertson
2 years ago
Do you have an actual product that has been tested and patented. Are there any actual uses currently during this phase and if so where and whos sing it now.
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HOW INVESTING WORKS
Cancel anytime before 48 hours before a rolling close or the offering end date.
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With Regulation A+, a non-accredited investor can only invest a maximum of 10% of their annual income or 10% of their net worth per year, whichever is greater. There are no restrictions for accredited investors.
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Hani Elshahawi
2 years ago
Interesting technology indeed. What price point do you anticipate at scale-$100 for single use may be OK for clinical settings but will be too high for remote patient monitoring (RPM) applications. Speaking of which, I have three more questions: 1) do you anticipate your biggest go-to-market to be in RPM? 2) Do you intend to add other sensing modalities or targets in the near-mid term or will you stay focused on breathing? 3) what has been the nature and form of your engagement with YC?
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